Our team

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Eleanor Howe, founder and CEO

Eleanor is a computational biologist with deep knowledge of the drug discovery and development processes. Diamond Age builds on Howe’s expertise in transcriptional profiling, a field in which she has worked since from its early days of small-scale microarray analysis.

Prior to founding Diamond Age, Howe served as the go-to bioinformatician in the Center for the Development of Therapeutics at the Broad Institute of MIT and Harvard, where she helped drive drug discovery projects in cancer, cardiovascular disease, and kidney disease, among others. She also worked at the Dana-Farber Cancer Institute, where she led mid- and late-stage development of the Multiexperiment Viewer – a powerful software tool for mining large genomic datasets – and the Institute for Genomic Research in Rockville, Maryland.

Howe earned a Ph.D. bioinformatics from Oxford University under Christopher Holmes and John Quackenbush, and holds a master’s degree in cellular and molecular biology from the University of Wisconsin-Madison and a bachelor’s degree in cellular and molecular biology from the University of Michigan. You can read her published scientific work here.

wFJt-RtJChris Friedline, consultant 

Chris brings a unique combination of expertise in IT and bioinformatics to Diamond Age. In his first career, he held several leadership positions in IT and systems engineering for a range of organizations including the Virginia Commonwealth University (VCU) Health System. He then became Director of Bioinformatics and IT at Granger Genetics, which used metagenomics methodologies to inform infection management, as well as other molecular tests to evaluate treatment effectiveness in acute lymphoblastic leukemia and other blood cancers.

Chris has an M.Bin in bioinformatics and a Ph.D. in integrative life sciences from VCU, where he also completed an NSF-funded postdoctoral fellowship in ecological genomics.

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Somdutta Saha, consultant

Somdutta is a computational biologist with expertise in structural bioinformatics and computational biology. Her interests span the translational spectrum, from early-stage drug discovery to clinical trial design, analysis, and follow-up. Having worked in both a large pharmaceutical company (GlaxoSmithKline) and a small biotech (Solid Biosciences), she brings diverse perspectives that allow her to quickly understand what Diamond Age clients need – and how to deliver it.

Somdutta holds a Ph.D. in Bioinformatics (computational chemistry) from the University of Arkansas for Medical Sciences, and a M.Sc. in bioinformatics from the West Bengal University of Technology.